Recent publications
22. Quantitative chemical imaging of organelles. P. Anees†, J. Tinker†, Y. Krishnan. Acc. Chem. Res., 57, 1906-1917 (2024) https://pubs.acs.org/doi/full/10.1021/acs.accounts.4c00191
21. A mechanism of lysosomal calcium entry M. Zajac, P. Anees†, S. Mukherjee†, D. Oettinger, K. Henn, J. Srikumar, J. Zou, A. Saminathan, Y. Krishnan. Sci. Adv., 10, eadk2317 (2024) (https://www.science.org/doi/abs/10.1126/sciadv.adk2317)
20. Detecting organelle-specific activity of potassium channels with a DNA nanodevice. P. Anees, A. Saminathan, E. R. Rozmus, D. Anke, A. B. Malik, B. P. Delisle, Y. Krishnan. Nat. Biotechnol. 2024 (https://doi.org/10.1038/s41587-023-01928-z)
19. A DNA nanodevice for mapping sodium at single organelle resolution. J. Zou, K. Mitra, P. Anees, D. Oettinger, J. Ramirez, A. T. Veetil, P. D. Gupta, R. Rao, J. J. Smith, P. Kratsios, Y. Krishnan. Nat. Biotechnol. 2024 (https://doi.org/10.1038/s41587-023-01950-1)
18. Passive endocytosis in model protocells. S. J. Zhang, L. A. Lowe, P. Anees, Y. Krishnan, T. G. Fai, J. W. Szostak, A. Wang. PNAS 2023 120, 2221064120. (https://www.pnas.org/doi/full/10.1073/pnas.2221064120)
17. Plasma membrane depolarization reveals endosomal escape incapacity of cell-penetrating peptides. M. Serulla, P. Anees, A. Hallaj, E. Trofimenko, T. Kalia, Y. Krishnan, C. Widmann. Eur. J. Pharm. Biopharm. 2023, 184, 116–124. (https://www.sciencedirect.com/science/article/pii/S093964112300019X)
16. Achieving Organelle-level Precision with Next-Generation Targeting Technologies. A. Saminathan†, M. Zajac†, P. Anees, Y. Krishnan. Nat. Rev. Mater., 2022, 7, 355-371. (https://www.nature.com/articles/s41578-021-00396-8)
15. Tissue-Specific Targeting of DNA Nanodevices in a Multicellular Living Organism. K. Chakraborty, P. Anees, S. Surana, S. Martin, J. Aburas, S. Moutel, F. Perez, S. P. Koushika, P. Kratsios, Y. Krishnan. Elife 10, e67830, 2021. (https://elifesciences.org/articles/67830)
14. Quantifying phagosomal HOCl at single immune-cell resolution. P. Anees, M. Zajac, Y. Krishnan. Methods in Cell Biology 164, 119-136 (2020). (https://www.sciencedirect.com/science/article/abs/pii/S0091679X20301898)
13. Surface vs. Core N/S/Se-Heteroatom Doping of Carbon Nanodots Produces Divergent Yet Consistent Optical Responses to Reactive Oxygen Species. X. Geng, T. R. Congdon, P. Anees, A. A. Greschner, F. Vetrone, M. A. Gauthier. Nanoscale Adv., 2020, 2, 4024-4033. (https://pubs.rsc.org/en/content/articlehtml/2020/na/d0na00439a)
12. Homogenous Scavenging Resolves Low-Purification Yield/Selectivity Caused by Secondary Binding of Protein-A to Antigen-Binding Antibody Fragments. P. Anees, M. A. Gauthier. Biomacromolecules 2020, 21, 825–829. (https://pubs.acs.org/doi/abs/10.1021/acs.biomac.9b01516)
11. Evidence, Manipulation, and Termination of pH ‘Nanobuffering’for Quantitative Homogenous Scavenging of Monoclonal Antibodies. P. Anees, Y. Zhao, A. A. Greschner, T. R. Congdon, H. W. de Haan, N. Cottyne, M. A. Gauthier. ACS Nano 2019, 13, 1019–1028. (https://pubs.acs.org/doi/full/10.1021/acsnano.8b07202)
10. A Ratiometric Near-Infrared Fluorogen for the Real Time Visualization of Intracellular Redox Status during Apoptosis. G. Saranya, P. Anees, M. M. Joseph, K. K. Maiti, A. Ajayaghosh. Chem. Eur. J., 2017, 23, 7191–7195. (https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201700839)
9. A Three-Photon Active Organic Fluorophore for Deep Tissue Ratiometric Imaging of Intracellular Divalent Zinc. D. S. Philips, S. Sreejith, T. He, N. V. Menon, P. Anees, J. Mathew, S. Sajikumar, Y. Kang, M. C. Stuparu, H. Sun, Y. Zhao, A. Ajayaghosh. Chem. Asian J., 2016, 11, 1523–1527. (https://onlinelibrary.wiley.com/doi/abs/10.1002/asia.201600170)
8. Self-assembly in sensor nanotechnology. P. Anees, V. K. Praveen, K. K. Kartha, A. Ajayaghosh. Comprehensive Supramolecular Chemistry II, for Volume 9 (2016), Elsevier Ltd, UK. (https://cir.nii.ac.jp/crid/1364233270233069184)
7. A Protein-Dye Hybrid System as Narrow Range Tunable Intracellular pH Sensor. P. Anees, K. V. Sudheesh, P. Jayamurthy, A. R. Chandrika, R. V. Omkumar, A. Ajayaghosh. Chem. Sci., 2016, 7, 6808−6814. (https://pubs.rsc.org/en/content/articlehtml/2016/sc/c6sc02659a)
6. Real Time Monitoring of Aminothiol Level in Blood Using a Near-Infrared Dye Assisted Deep Tissue Fluorescence and Photoacoustic Bimodal Imaging. P. Anees, J. Joseph, S. Sreejith, N. V. Menon, S. W. K. Yu, Y. Kang, A. Ajayaghosh, Y. Zhao. Chem. Sci., 2016, 7, 4110−4116. (https://pubs.rsc.org/en/content/articlehtml/2016/sc/c5sc04986e)
5. A squaraine based fluorescent probe and a process for the preparation thereof. P. Anees, A. Ajayaghosh, (2017) US patent, US9791451B2 (https://patents.google.com/patent/US9791451B2/en)
4. Near-IR Squaraine Dye–Loaded Gated Periodic Mesoporous Organosilica for Photo-Oxidation of Phenol in a Continuous-Flow Device. P. Anees, P. Borah, S. Sreejith, N. V. Menon, Y. Kang, A. Ajayaghosh, Y. Zhao. Sci. Adv.,2015;1:e1500390. (https://www.science.org/doi/abs/10.1126/sciadv.1500390)
3. Self-assembled Near-Infrared Dye Nanoparticles as a Selective Protein Sensor by Activation of a Dormant Fluorophore. P. Anees, S. Sreejith, A. Ajayaghosh. J. Am. Chem. Soc., 2014, 136, 13233−13239. (https://pubs.acs.org/doi/full/10.1021/ja503850b)
2. Heteroaromatic Donors in Donor–Acceptor–Donor Based Fluorophores Facilitate Zinc Ion Sensing and Cell Imaging. S. Sreejith, K. P. Divya, P. Jayamurthy, J. Mathew, V. N. Anupama, D. S. Philips, P. Anees, A. Ajayaghosh. Photochem. Photobiol. Sci., 2012, 11, 1715–1723. (https://pubs.rsc.org/en/content/articlelanding/2012/pp/c2pp25110h/unauth)
1. A Zn2+-Specific Fluorescent Molecular Probe for the Selective Detection of Endogenous Cyanide in Biorelevant Samples. K. P. Divya, S. Sreejith, B. Balakrishna, P. Jayamurthy, P. Anees, A. Ajayaghosh. Chem. Commun., 2010, 46, 6069–6071. (https://pubs.rsc.org/en/content/articlehtml/2010/cc/c0cc01159b)